The unicellular ancestry of animals

Before
animals

Life was unicellular.

Enter the story

Live microscopy · Multicellgenome Lab

01 / THE QUESTION

Then something
extraordinary happened.

A new way of living became possible.

A GLIMPSE / 01

Cells started
to cooperate.

Capsaspora owczarzaki

A GLIMPSE / 02

And they coordinated
in time.

Ichthyosporea

Atmospheric artistic interpretation of an early marine animal form

A NEW LINEAGE

From this unicellular world,
animals emerged.

OUR MISSION

Decoding the animal
operating system.

We study the closest unicellular relatives of animals — discovering and cultivating new species, analyzing their genomes and comparing them experimentally — to decode how the first animals evolved.

Explore the origins of the animal toolkit ↗

02 / THE ORGANISMS

Several organisms.
One evolutionary question.

Five main experimental systems sit at the centre of our current research. Beyond them, organisms we helped isolate, describe, culture or sequence extend a platform now being developed across an international community.

Simplified phylogenetic tree showing Metazoa and their closest unicellular relativesEvolutionary framework

Main experimental systems

At the centre of our current experimental programme

Beyond the main systems

Organisms we helped establish, now being extended across the field

03 / MISSING RELATIVES

The tree
is incomplete.

Recent discoveries reveal how much of the unicellular tree surrounding animals remains unseen. Entire branches are known only from environmental DNA. Now we are looking for the organisms.

Explore the missing lineages ↗
01FRESHIP102FRESHIP203MAOP104MAOP205MACHO406CLADE L07HOL108OPI109HOL210HOL311HOL4

KNOWN UNKNOWNS / UNKNOWN UNKNOWNS

Searching across
the living planet.

Marine waters, freshwater ecosystems, soils and animal-associated habitats may contain lineages capable of changing how we understand animal origins.

Earth seen from space, representing the global search for missing unicellular relatives of animals
THE SEARCHFrom DNA
to culture.

Detect. Visualize. Isolate. Culture. Sequence. Experiment.

Explore the lineages now. Published detections will be connected to their places and environments as the atlas develops.Open the lineage explorer ↗

04 / DISCOVERIES

We built the toolkit
to ask the question.

20+years reconstructing animal origins

5main experimental systems

3new species described

1comparative platform for animal origins

Explore discoveries ↗

05 / FIELD-BUILDING

We didn’t just build
model systems.
We helped build a field.

Former members now lead laboratories, hold faculty and research positions, develop new methods and open new directions across animal origins and eukaryotic diversity.

13Independent labs — and counting

+New questions

+An expanding network

Explore the alumni network ↗

ANIMAL ORIGINS PORTAL

Explore the living
archive before animals.

Organisms, movies, life cycles, experimental tools, genomes, discoveries and resources — connected through the tree.